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Recombinant Human Amphiregulin (RMPP-00231070)

Cat. No.: RMPP-00231070

Category: Growth Factors & Cytokines

INQUIRY 10 μg 50 μg
Amphiregulin is an EGF related growth factor that signals thro μgh the EGF/TGF-α receptor, and stimulates growth of keratinocytes, epithelial cells and some fibroblasts. Amphiregulin also inhibits the growth of certain carcinoma cell lines. Synthesized as a transmembrane protein, Amphiregulin’s extracellular domain is proteolytically processed to release the mature protein. There are 6 conserved cysteine residues, which form 3 intramolecular disulfide bonds essential for biological activity. Recombinant Human Amphiregulin is an 11.3 kDa glycoprotein consisting of 98 amino acid residues.

Product Features

Source E.coli
Purity ≥ 95% by SDS-PAGE gel and HPLC analyses.
Nature Recombinant
Endotoxin Level < 1 Eu/μg
Cross Reactivity Human, Mouse

Protein Information

UniProt ID P15514
Molecular Weight 11.3 kDa

Storage & Shipping

Shipping and Storage Shipped on Dry Ice.

For research use only. Not for clinical use.