A 83-01 (RMML-00120058)
Cat. No.: RMML-00120058
Category: Inhibitors & Activators
INQUIRY
1 mg
5 mg
A 83-01 is a potent inhibitor of activin receptor-like kinase. Facilitates the conversion of epiblast stem cells to the naїve pluripotent state. In combination with PD0325901, enables OCT4-mediated reprogramming. Inhibits mesoderm and endoderm specification. Disrupts epithelial to mesenchymal transition throμgh inhibition of the SMAD signaling pathway.
Product Features
| Purity | ≥ 95% |
|---|---|
| Applications | Differentiation, Maintenance, Reprogramming |
| Cross Reactivity | Human, Mouse, Non-Human Primate, Other, Rat |
Compound Information
| Target Pathways | Activin/Nodal/TGFβ |
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| CAS Number | 909910-43-6 |
| Molecular Formula | C₂₅H₁₉N₅S |
Storage & Shipping
| Handling | Refer to SDS for further information. |
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For research use only. Not for clinical use.