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Bone Tissue Development Service

Bone Tissue Development Service

Bone tissue engineering aims to induce new functional bone regeneration through a synergistic combination of biomaterials, cells and factor therapies. Engineered bone tissues are considered a potential alternative to conventional bone grafts because they are in unlimited supply and do not transmit disease. In response to this market demand, CD BioSciences has launched a bone tissue development service.

Overview of Bone Tissue Engineering

Fig 1. Bone Tissue

Bone defects are very common in clinical practice and are difficult to treat. Traditional treatment methods generally use autologous bone grafting, allogeneic bone grafting, and artificial bone material replacement. However, all of these methods have different degrees of limitations, such as immune rejection and uncertainty of osteogenic ability. With the development of tissue engineering, the construction of tissue-engineered scaffolds and the action of growth factors can restore diseased or damaged bone tissue to its natural state, thus providing technical support and security for the clinical treatment of bone defects.

  • Process of Bone Tissue Engineering
    By growing isolated cells, expanded by in vitro culture on a natural or synthetic cell scaffold, they can grow into bone tissue. This biomaterial scaffold provides a three-dimensional space for the cells to survive, facilitating access to sufficient nutrients, gas exchange, and waste elimination. The cells are grown on a preformed three-dimensional scaffold and can subsequently be implanted in the bone defect site, repairing the bone tissue defect while the biomaterial gradually degrades.

Fig 2. Bone Tissue Engineering

Bone Tissue Engineering

Challenges in Bone Tissue Engineering

Bone tissue engineering is currently recognized as one of the research areas with the greatest potential for practical clinical benefit. Seed cells are now abundantly sourced and their in vitro large-scale expansion technology is gradually maturing. Biomaterials continues to be new biomimetic and intelligent. These factors have shortened the time frame for tissue-engineered bone constructs to be used in the clinic. However, at present, due to the immaturity of science and technology, the simultaneous construction of vascularized and neutralized tissues still needs further research, which is a critical link in the transformation of bone tissue engineering from basic to clinical applications.

Fig 3. Challenges in Bone Tissue Engineering

Applications of Tissue-engineered Bone

  • Bone Defect Treatment
    Bone loss due to trauma, infection, tumor removal, or congenital disease creates a large gap in the bone called a bone defect. Building bone tissue and repairing bone defects in vivo is the ultimate goal of bone tissue research.
  • Maxillofacial Defects Treatment
    The results of numerous studies have shown that tissue-engineered bone products can be used to treat maxillofacial defects, such as trauma to the head, neck and facial region.

Our Services

CD BioSciences provides bone tissue development services. Based on our strong research team and abundant raw materials, we can provide various combinations to explore the preparation of artificial bone tissues.

  • Seed Cell Culture
  • Growth Factor Combination Screening
  • Scaffold Customization

As a pioneer in biotechnology, CD BioSciences has grown into one of the largest independent biotechnology companies in the world. CD BioSciences is committed to providing professional and efficient service to our customers around the world. If you are interested in our service, please contact us.

For research use only, not for clinical use.