Cartilage Tissue Development Service
Damage to cartilage tissue is irreversible and therefore requires replacement after cartilage damage has occurred. Cartilage tissue engineering offers more possibilities for articular cartilage replacement. Based on cartilage tissue engineering technology, CD BioSciences offers cartilage tissue development services.
Introduction to Cartilage Tissue Engineering
The key to tissue-engineered cartilage fabrication is the expansion of seed cells, three-dimensional culture of cells, and the addition of exogenous stimuli, such as chemical growth factors, hydrodynamics, and hypoxia. The cartilage seeds are grown on biodegradable, histocompatibility biomaterial to form a complex, which is then implanted into the cartilage defect. As the biomaterial degrades on its own, the implanted cells form new cartilage to fill the defect.
Applications of Cartilage Tissue Engineering
Osteoarthritis and joint pain are caused by damage to joint cartilage. Once a joint wears out, the rate of repair never catches up with the rate of wear. The main treatments for joint damage are conservative treatments, such as oral medications, steroid injections, hyaluronic acid injections, and surgical treatments, which involve replacing the patient's artificial joints. However, none of these therapies can completely solve the patient's pain, so there is a need to develop better therapies, such as cartilage tissue engineering for the treatment of related diseases.
Cartilage tissue engineering can theoretically provide the most optimal repair graft for any cartilage defect. It can be used in orthopedic or joint surgery to repair cartilage defects on the joint surface or in the meniscus region to enable reconstruction of joint motion function.
Tissue-engineered cartilage can also be used in orthopedic or head and neck surgery to repair cartilage defects with specific form and function in the auricle, trachea, eyelids, nose, and larynx.
Challenges in Cartilage Tissue Engineering
Tissue-engineered articular cartilage has good research prospects in cartilage injury, but there is still a considerable distance between tissue-engineered articular cartilage and clinical requirements. There is a need to improve techniques for rapid and massive proliferation of chondrocytes and to develop techniques for vascularization of scaffold materials. Maintenance of growth factor expression and development of practical cartilage scaffold materials are also important directions for research.
Our Services
CD BioSciences offers cartilage tissue development services, including seed cell expansion culture, exogenous stimulator addition and scaffold material screening, as well as other R&D services. Based on our wide range of raw materials, we can provide various combinations to explore the preparation of artificial cartilage tissue.
- Seed Cell Isolation & Culture
We provide experiments for in vitro isolation, culture and identification of seed cells. Multiple exogenous stimuli are randomly combined in order to find the optimal culture condition. - Cartilage Tissue Engineering Scaffold Customization
Scaffolds made with different raw materials can lead to different tissue growth results.
As a pioneer in biotechnology, CD BioSciences has grown into one of the largest independent biotechnology companies in the world. CD BioSciences is committed to providing professional and efficient service to our customers around the world. If you would like more information, please contact us.
For research use only, not for clinical use.
