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Ocular Disease Stem Cell Therapy Development

Ocular Disease Stem Cell Therapy Development

The eyes are a vital sensory organ, providing us with the ability to perceive the world around us. Unfortunately, a wide range of ocular diseases can affect the eyes, leading to vision impairment or even blindness. Traditional treatments for many of these diseases have limitations, but the field of regenerative medicine offers promising avenues for addressing the root causes and potentially restoring vision. Stem cell therapy, in particular, has emerged as an innovative approach for treating ocular diseases. CD BioSciences offers stem cell therapy development services for ocular diseases, based on out advanced technology and professional team.

Eye disease icons

Introduction into Ocular Diseases

The anatomy of the eyeThe anatomy of the eye (Tomczak W, et al., 2023)

Ocular diseases encompass a diverse array of conditions that affect the structure and function of the eye. These diseases can affect the cornea, lens, retina, optic nerve, and other vital components of the visual system.

Common ocular diseases include but are not limited to conditions such as glaucoma, cataracts, age-related macular degeneration, diabetic retinopathy, retinal detachment, keratitis, conjunctivitis (pink eye), and many others. These conditions can affect different parts of the eye, including the cornea, retina, lens, optic nerve, and the surrounding structures, leading to a variety of symptoms and visual disturbances.

Stem Cell Therapy for Ocular Disease

The use of stem cells (SC) has emerged as a promising avenue in the field of ophthalmology, offering potential therapeutic solutions for a wide range of visual impairments and degenerative eye diseases.SC have a unique ability to self-renew and differentiate into specialized cell types, making them a valuable tool for repairing damaged tissues and restoring visual function.

Clinical trials of hESC- and iPSC-based studies in retinal therapy

CONDITION STEM CELL TYPE DELIVERY MECHANISM
Stargardt macular dystrophy hESC-RPE Subretinal injection
Dry AMD hESC-RPE Subretinal injection
hESC-RPE monolayer Subretinal implantation, scaffold
iPSC-RPE Subretinal implantation, scaffold
Wet AMD iPSC-RPE sheet Subretinal implantation
Various retinal degenerative and ischemic conditions CD34+ bone marrow stem cells Intravitreal injection
Central retinal vein occlusion CD34+ bone marrow stem cells Intravitreal injection
Retinitis pigmentosa CD34+ bone marrow stem cells Intravitreal injection
Allogeneic fetal retinal progenitor cell Intravitreal injection

The promise of ocular regenerative medicine derives from the differentiate ability of stem cells. In the eyes, stem cells are utilized to replace tissue that are damaged by degeneration, trauma or ischemia. In the posterior pole the eye, stem cells replace damaged cells in the retina, retinal pigment epithelium, and optic nerve. Additionally, stem cells have potential for replacing supportive tissues, such as glial cells.

Our Services

CD BioSciences offers stem cell therapy development service based on our advanced technology and professional team. Our stem cell therapy development services are offered in ocular diseases included but not limited as follows:

Corneal Disorders

  • Corneal dystrophies
  • Corneal scarring
  • Limbal stem cell deficiency

Retinal Diseases

  • Age-related macular degeneration (AMD)
  • Retinitis pigmentosa
  • Stargardt disease
  • Retinal degeneration

Ocular Surface Disorders

  • Dry eye syndrome
  • Sjögren's syndrome
  • Ocular cicatricial pemphigoid

Optic Nerve Disorders

  • Glaucomatous optic neuropathy
  • Optic nerve atrophy

Corneal Injuries

  • Chemical burns
  • Thermal burns
  • Traumatic corneal injuries

Retinal Vascular Disorders

  • Diabetic retinopathy
  • Retinal vein occlusion

Corneal Neovascularization

  • Conditions leading to excessive blood vessel growth in the cornea

As a pioneer in biotechnology, CD BioSciences has grown into one of the largest independent biotechnology companies in the world. CD BioSciences is committed to providing professional and efficient service to our customers around the world. If you are interested in our service, please contact us.

Reference

  1. Tomczak W, Winkler-Lach W, Tomczyk-Socha M, Misiuk-Hojło M. Advancements in Ocular Regenerative Therapies. Biology. 2023; 12(5):737.

For research use only, not for clinical use.