Induced Pluripotent Stem Cell Therapy Development

Induced pluripotent stem cells (iPSCs) are a type of stem cell that can be generated from adult cells, such as skin cells or blood cells, through reprogramming techniques. iPSCs have the ability to differentiate into any cell type in the body, similar to embryonic stem cells. This makes them a promising tool for regenerative medicine, as they can potentially be used to replace damaged or diseased cells and tissues. CD BioSciences offers iPSC therapy development services for multiple diseases and disorders, dedicating to advancing the therapeutic development of them.

About iPSC Therapy

Induced pluripotent stem cell (iPSC) therapy is a type of regenerative medicine that involves the use of iPSCs for the treatment of various diseases and injuries. iPSC therapy is based on the ability of iPSCs to differentiate into any cell type in the body, which makes them a promising tool for regenerating damaged or diseased tissues.

Progress in therapies based on iPSC (Rowe, et al., 2019)

Approaches for iPSC Therapy

• Direct Cell Replacement
  iPSCs can be differentiated into the desired cell type and then transplanted into the patient to replace damaged or diseased cells. For example, iPSCs can be differentiated into cardiomyocytes and used to regenerate damaged heart tissue.
• Gene Editing
  iPSCs can be genetically edited to correct mutations that cause genetic diseases. The corrected iPSCs can then be differentiated into the desired cell type and transplanted into the patient.
• Drug Discovery
  iPSCs can be used to model disease in vitro, allowing for the development and testing of new drugs.
• Tissue Engineering
  iPSCs can be used to engineer tissues or organs for transplantation, potentially eliminating the need for donor organs.

Applications of iPSC Therapy

There are many potential applications for induced pluripotent stem cell (iPSC) therapy, and several clinical trials are currently underway to test its efficacy for various diseases and conditions.

Parkinson's disease: iPSCs can be used to generate dopamine-producing neurons, which are lost in Parkinson's disease.

Heart diseases: iPSCs can be used to generate cardiomyocytes, the cells that make up the heart muscle. These cells could be used to regenerate damaged heart tissue following a heart attack, or to replace heart tissue damaged by disease.

Diabetes: iPSCs can be used to generate insulin-producing pancreatic beta cells, which are lost in type 1 diabetes. These cells could be transplanted into diabetic patients to restore insulin production.

Spinal cord injury: iPSCs can be used to generate neural cells that could be used to repair damaged spinal cord tissue following injury.

Age-related macular degeneration: iPSCs can be used to generate retinal pigment epithelial cells, which are lost in age-related macular degeneration. These cells could be transplanted into patients to restore vision.

Our Services

CD Biosciences offers therapy development services of induced pluripotent stem cells, which represent a promising tool for regenerative medicine and have the potential to revolutionize the treatment of a wide range of diseases and injuries.

Workflow of iPSC Therapy Development

Drug Discovery

Disease Modeling

Drug Safety Assays

Cell-based Therapy

As a pioneer in biotechnology, CD BioSciences has grown into one of the largest independent biotechnology companies in the world. CD BioSciences is committed to providing professional and efficient service to our customers around the world. If you are interested in our service, please contact us.

Reference

1. Rowe, R Grant, and George Q Daley. "Induced pluripotent stem cells in disease modelling and drug discovery." Nature reviews. Genetics vol. 20,7 (2019): 377-388.