Periodontal Tissue Development Service

Periodontal tissue is the collection of tissues that anchor teeth to bone, and periodontitis compromises the integrity and function of periodontal tissue. This highly prevalent inflammatory disease is clinically treatable, but healing outcomes are inconsistent with functional periodontal tissues. Tissue engineering offers a better solution for this disease. With the support of tissue engineering technology, CD BioSciences has launched a periodontal tissue development service.

Overview of Periodontal Tissue Engineering

Periodontitis is a globally recognized disease that is an inflammation of periodontal tissue caused by bacterial infection, resulting in alveolar bone loss. Once it occurs, the damaged tissue cannot be restored to its original state. Periodontal tissue engineering is the regeneration of periodontal wounds by stimulating the self-healing capacity of periodontal tissues. Periodontal regeneration is the complete reconstruction of the damaged attachment apparatus, both hard and soft tissues. The right combination of appropriate cell types, biochemical stimulators and provision of a stable matrix can drive the regeneration of both soft and hard periodontal tissues.

Periodontal Tissue Regeneration (Galli, M. et al. 2021)

• Process of Periodontal Tissue Engineering
  Periodontal tissue engineering in a broad sense refers to the use of stem cells cultured in vitro, combined with certain biological scaffold materials through different strategies and methods, and implanted in vivo to promote or achieve regeneration of periodontal tissues. Relevant target seed cells are obtained in vivo, expanded in vitro and then inoculated onto biocompatible natural or synthetic cell scaffolds. At the same time, growth factors are provided microenvironment. After a certain period of continued in vivo or in vitro culture, new tissue can be formed through cellular self-renewal and cell-to-cell interactions.

Challenges in Periodontal Tissue Engineering

The reconstruction of periodontal tissues is complex and requires not only that the new bone, osseous and periodontal fibers have an arrangement similar to that of natural tissues, but also that all three works in synergy with each other. The rate of stent degradation and the rate of periodontal tissue regeneration also need to be matched. In addition, the ethical issue of the source of adult stem cells used for periodontal regeneration is also an aspect that needs to be regulated.

Applications of Tissue-engineered Periodontium

The ultimate goal of periodontitis treatment is to obtain good regeneration of the destroyed or even missing periodontal tissues. Periodontal tissue engineering technology has great potential and broad application prospects for the restoration and regeneration of periodontal defects in treatment. The optimal combination and combination of seed cells, growth factors, and scaffold materials have been successfully used in animal experimental models to achieve the regeneration of periodontal tissue form, structure, and function. This provides the theoretical basis and scientific basis for clinical treatment of periodontal disease.

Our Services

CD BioSciences offers periodontal tissue development services, including but not limited to seed cell culture, expansion, and induction of differentiation. Depending on your research needs, we also offer 3D scaffold customization services. Based on our professional laboratory team, we can work with you to solve your artificial periodontal tissue development problems.

As a pioneer in biotechnology, CD BioSciences has grown into one of the largest independent biotechnology companies in the world. CD BioSciences is committed to providing professional and efficient service to our customers around the world. If you are interested in our service, please contact us.

Reference

1. Galli, M. et al. (2021). Current and future trends in periodontal tissue engineering and bone regeneration.