Organoid Development Services
Animal models have facilitated the development of disease treatment strategies that enable the study of pathology without involving human patients. However, insights from animal models are not guaranteed to be applicable to human tissues. Organoids have become a new tool of interest because of their physiological properties and structure similar to those of in vivo tissues and organs. CD BioSciences offers a variety of organoid development services to facilitate the rapid development of related fields such as disease research.
Organoids as Improved Model for Disease Research
Organoids more accurately model human gut function and physiology than animal models or 2D models. Organoids are models with a three-dimensional structure consisting of pluripotent tissue-specific stem cells and their more differentiated progeny.
Currently, organoids have been shown to be widely used in experimental settings. Because they are compatible with routinely used imaging techniques as well as live cell imaging, and are capable of metabolic activity assessment, genome-wide expression, protein analysis, gene editing, and high-throughput assays. As a result, organoids are increasingly used to study organ tissue function, model disease phenotypes, and drug discovery screens.
Elements for Organoids Culture
Organoids are derived from pluripotent stem cells or adult stem cells, also known as tissue stem cells. Typically, the process of organoid formation involves several key points. First, activation or inhibition of key signaling pathways that regulate developmental patterns to properly establish the direction of stem cell differentiation. Secondly, the development of a medium containing growth factors and nutrients to meet the normal growth and differentiation of all cell types within the organoid. Finally, to provide three-dimensional growth space for cell aggregation by embedding three-dimensional scaffolds.
Process for the establishment of human PSC-derived and AdSC-derived organoids. (Jihoon Kim, et al., 2020)
Our Services
CD Biosciences offers organoid development services. The ability of organoids to accurately reproduce the body's internal environment and cellular interactions makes them important for use in basic research and disease studies. Our services include, but are not limited to, tissue processing, specimen activity analysis, organoid culture, passaged amplification, organoid identification, and more. Based on our professional laboratory team, we can work with you to solve your organoid-related research problems.
Features of Our Services
CD BioSciences has a wide range of cellular materials, scaffold materials and various reagents.
In the help of a professional team, can get your results within your expectations.
To free you from hassles, we offer a one-stop service.
As a pioneer in biotechnology, CD BioSciences has grown into one of the largest independent biotechnology companies in the world. CD BioSciences is committed to providing professional and efficient service to our customers around the world. If you are interested in our service, please contact us.
Reference
- Jihoon Kim, et al. (2020). Human organoids: model systems for human biology and medicine. Nature Reviews Molecular Cell Biology. 21, pages571–584.
For research use only, not for clinical use.
