Anti-14-3-3 alpha + beta Antibody (RMAB-0250015)
Cat. No.: RMAB-0250015
Category: Primary Antibodies
INQUIRY
100 μL
1 mL
Rabbit monoclonal to 14-3-3 alpha + beta
Product Features
| Isotype | IgG |
|---|---|
| Clonality | Monoclonal |
| Host Species | Rabbit |
| Clone Number | Y62 |
| Form | Liquid |
| Purity | Protein A purified |
| Species Reactivity | Human |
| Immunogen | Synthetic peptide within Human 14-3-3 alpha + beta aa 2-3 (C terminal). The exact sequence is proprietary. |
| Applications | WB, IHC-P, ICC/IF |
| Key Features | Produced recombinantly (animal-free) for high batch-to-batch consistency and long term security of supply; Rabbit monoclonal to 14-3-3 alpha + beta; Suitable for: WB, IHC-P, ICC/IF; Reacts with: Human |
Target Information
| Target Symbol | YWHAB |
|---|---|
| Target Name | 14-3-3 protein beta/alpha |
| UniProt ID | P31946 |
| Cellular Localization | Cytoplasm. Melanosome. Identified by mass spectrometry in melanosome fractions from stage I to stage IV. |
| Function | Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. Negative regulator of osteogenesis. |
| Post-translational Modifications | The alpha, brain-specific form differs from the beta form in being phosphorylated. Isoform Short contains a N-acetylmethionine at position 1. |
| Sequence Similarities | Belongs to the 14-3-3 family. |
Storage & Shipping
| Storage Buffer | pH: 7.20; Preservative: 0.01% Sodium azide; Constituents: 49% PBS, 50% Glycerol (glycerin, glycerine), 0.05% BSA |
|---|---|
| Storage & Shipping | Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. |
For research use only. Not for clinical use.
