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Anti-14-3-3 beta Antibody (RMAB-0250018)

Cat. No.: RMAB-0250018

Category: Primary Antibodies

INQUIRY 100 μL 10 µL
Rabbit monoclonal to 14-3-3 beta

Product Features

Isotype IgG
Clonality Monoclonal
Host Species Rabbit
Clone Number 6F6
Form Liquid
Purity Affinity purified
Species Reactivity Human, Mouse, Rat
Immunogen Synthetic peptide corresponding to Human 14-3-3 beta.
Applications Flow Cyt (Intra), ICC/IF, WB
Key Features Produced recombinantly (animal-free) for high batch-to-batch consistency and long term security of supply; Rabbit monoclonal to 14-3-3 beta; Suitable for: Flow Cyt (Intra), ICC/IF, WB; Reacts with: Mouse, Rat, Human

Target Information

Target Symbol YWHAB
Target Name 14-3-3 protein beta/alpha
UniProt ID P31946
Cellular Localization Cytoplasm. Melanosome. Identified by mass spectrometry in melanosome fractions from stage I to stage IV.
Function Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. Negative regulator of osteogenesis.
Post-translational Modifications The alpha, brain-specific form differs from the beta form in being phosphorylated. Isoform Short contains a N-acetylmethionine at position 1.
Sequence Similarities Belongs to the 14-3-3 family.

Storage & Shipping

Storage Buffer pH: 7.40; Preservative: 0.02% Sodium azide; Constituents: 49.19% PBS, 0.79% Sodium chloride, 50% Glycerol (glycerin, glycerine)
Storage & Shipping Shipped at 4°C. Store at 4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.

For research use only. Not for clinical use.