Anti-ABCG2/Bcrp Rabbit Monoclonal Antibody (RMAB-0251348)
Cat. No.: RMAB-0251348
Category: Primary Antibodies
Research Area: Cancer Research, Stem Cells
INQUIRY
100 μL
Customer Size
Anti-ABCG2/Bcrp Rabbit Monoclonal Antibody. Tested in WB applications. This antibody reacts with Human.
Product Features
| Isotype | IgG |
|---|---|
| Clonality | Monoclonal |
| Host Species | Rabbit |
| Form | Liquid |
| Species Reactivity | Human |
| Applications | WB, Flow Cyt, IHC, IF, ICC |
Target Information
| Target Symbol | ABCG2 |
|---|---|
| Target Name | Broad substrate specificity ATP-binding cassette transporter ABCG2 |
| UniProt ID | Q9UNQ0 |
| Function | Xenobiotic transporter that may play an important role in the exclusion of xenobiotics from the brain. May be involved in brain-to-blood efflux. Appears to play a major role in the multidrug resistance phenotype of several cancer cell lines. When overexpressed, the transfected cells become resistant to mitoxantrone, daunorubicin and doxorubicin, display diminished intracellular accumulation of daunorubicin, and manifest an ATP-dependent increase in the efflux of rhodamine 123. |
Storage & Shipping
| Storage Buffer | Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles. |
|---|---|
| Storage & Shipping | Dry Ice |
For research use only. Not for clinical use.
