Anti-Albumin Antibody (RMAB-0250051)
Cat. No.: RMAB-0250051
Category: Primary Antibodies
INQUIRY
100 μL
Customer Size
Rabbit monoclonal to Albumin
Product Features
| Isotype | IgG |
|---|---|
| Clonality | Monoclonal |
| Host Species | Rabbit |
| Clone Number | EPR20195 |
| Form | Liquid |
| Purity | Protein A purified |
| Species Reactivity | Human, Mouse, Rat |
| Immunogen | Full length native protein (purified) corresponding to Human Albumin aa 1 to the C-terminus. (Purified Proteins from Normal Serum). |
| Applications | Flow Cyt (Intra), WB, IP, ICC/IF |
| Key Features | Produced recombinantly (animal-free) for high batch-to-batch consistency and long term security of supply; Rabbit monoclonal to Albumin; Suitable for: Flow Cyt (Intra), WB, IP, ICC/IF; Reacts with: Mouse, Rat, Human |
Target Information
| Target Symbol | ALB |
|---|---|
| Target Name | Albumin |
| UniProt ID | P02768 |
| Cellular Localization | Secreted. |
| Function | Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 8% of all plasma zinc. |
| Involvement in Disease | Defects in ALB are a cause of familial dysalbuminemic hyperthyroxinemia (FDH). FDH is a form of euthyroid hyperthyroxinemia that is due to increased affinity of ALB for T(4). It is the most common cause of inherited euthyroid hyperthyroxinemia in Caucasian population. |
| Post-translational Modifications | Kenitra variant is partially O-glycosylated at Thr-62. It has two new disulfide bonds Cys-6 to Cys-62 and Cys-61 to Cys-66. Glycated in diabetic patients. Phosphorylation sites are present in the extracelllular medium. Acetylated on Lys-223 by acetylsalicylic acid. |
| Sequence Similarities | Belongs to the ALB/AFP/VDB family. Contains 3 albumin domains. |
Storage & Shipping
| Storage Buffer | pH: 7.2; Preservative: 0.01% Sodium azide; Constituents: 59% PBS, 40% Glycerol, 0.05% BSA |
|---|---|
| Storage & Shipping | Shipped at 4°C. Store at 4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. |
For research use only. Not for clinical use.
