Anti-CD16a Antibody - C-terminal (RMAB-0250232)
Cat. No.: RMAB-0250232
Category: Primary Antibodies
INQUIRY
100 μL
1 mL
Rabbit monoclonal to CD16a - C-terminal
Product Features
| Isotype | IgG |
|---|---|
| Clonality | Monoclonal |
| Host Species | Rabbit |
| Clone Number | SP189 |
| Form | Liquid |
| Purity | Protein A/G purified |
| Species Reactivity | Human |
| Immunogen | Synthetic peptide. |
| Applications | WB, IHC-P, Flow Cyt (Intra) |
| Key Features | Produced recombinantly (animal-free) for high batch-to-batch consistency and long term security of supply; Rabbit monoclonal to CD16a - C-terminal; Suitable for: WB, IHC-P, Flow Cyt (Intra); Reacts with: Human |
Target Information
| Target Symbol | FCGR3A |
|---|---|
| Target Name | Low affinity immunoglobulin gamma Fc region receptor III-A |
| UniProt ID | P08637 |
| Cellular Localization | Cell membrane. Secreted. Exists also as a soluble receptor. |
| Function | Receptor for the Fc region of IgG. Binds complexed or aggregated IgG and also monomeric IgG. Mediates antibody-dependent cellular cytotoxicity (ADCC) and other antibody-dependent responses, such as phagocytosis. |
| Involvement in Disease | Immunodeficiency 2 |
| Post-translational Modifications | Glycosylated. Contains high mannose- and complex-type oligosaccharides. Glycosylation at Asn-18 is mandatory for high affinity binding to the Fc and for discrimination between fucosylated and afucosylated IgG glycoforms. The soluble form is produced by a proteolytic cleavage. |
| Sequence Similarities | Contains 2 Ig-like C2-type (immunoglobulin-like) domains. |
Storage & Shipping
| Storage Buffer | pH: 7.60; Preservative: 0.1% Sodium azide; Constituents: PBS, 1% BSA |
|---|---|
| Storage & Shipping | Shipped at 4°C. Store at 4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. |
For research use only. Not for clinical use.
