Anti-CD20 Antibody (RMAB-0250252)
Cat. No.: RMAB-0250252
Category: Primary Antibodies
INQUIRY
100 μL
1 mL
Rabbit monoclonal to CD20
Product Features
| Isotype | IgG |
|---|---|
| Clonality | Monoclonal |
| Host Species | Rabbit |
| Clone Number | SP32 |
| Form | Liquid |
| Purity | Protein A/G purified |
| Species Reactivity | Human, Mouse, Rat |
| Immunogen | Synthetic peptide within Human CD2 aa 25 to the C-terminus. The exact sequence is proprietary. |
| Applications | Flow Cyt (Intra), WB, mIHC, IHC-P, ICC/IF |
| Key Features | Produced recombinantly (animal-free) for high batch-to-batch consistency and long term security of supply; Rabbit monoclonal to CD20; Suitable for: Flow Cyt (Intra), WB, mIHC, IHC-P, ICC/IF; Reacts with: Mouse, Rat, Human |
Target Information
| Target Symbol | MS4A1 |
|---|---|
| Target Name | B-lymphocyte antigen CD20 |
| UniProt ID | P11836 |
| Cellular Localization | Membrane. |
| Function | This protein may be involved in the regulation of B-cell activation and proliferation. |
| Involvement in Disease | Defects in MS4A1 are the cause of immunodeficiency common variable type 5 (CVID5); also called antibody deficiency due to CD2 defect. CVID5 is a primary immunodeficiency characterized by antibody deficiency, hypogammaglobulinemia, recurrent bacterial infections and an inability to mount an antibody response to antigen. The defect results from a failure of B-cell differentiation and impaired secretion of immunoglobulins; the numbers of circulating B cells is usually in the normal range, but can be low. |
| Post-translational Modifications | Phosphorylated. Might be functionally regulated by protein kinase(s). |
| Sequence Similarities | Belongs to the MS4A family. |
Storage & Shipping
| Storage Buffer | pH: 7.60; Preservative: 0.1% Sodium azide; Constituents: PBS, 1% BSA |
|---|---|
| Storage & Shipping | Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. |
For research use only. Not for clinical use.
