Anti-CD3D Antibody (RMAB-0250339)
Cat. No.: RMAB-0250339
Category: Primary Antibodies
INQUIRY
100 μL
Customer Size
Rabbit monoclonal to CD3D
Product Features
| Isotype | IgG |
|---|---|
| Clonality | Monoclonal |
| Host Species | Rabbit |
| Clone Number | EP4426 |
| Form | Liquid |
| Purity | Protein A purified |
| Species Reactivity | Human |
| Immunogen | Synthetic peptide. |
| Applications | Flow Cyt, WB, IP, IHC-P, ICC/IF |
| Key Features | Produced recombinantly (animal-free) for high batch-to-batch consistency and long term security of supply; Rabbit monoclonal to CD3D; Suitable for: Flow Cyt, WB, IP, IHC-P, ICC/IF; Reacts with: Human |
Target Information
| Target Symbol | CD3D |
|---|---|
| Target Name | T-cell surface glycoprotein CD3 delta chain |
| UniProt ID | P04234 |
| Cellular Localization | Membrane. |
| Function | The CD3 complex mediates signal transduction. |
| Involvement in Disease | Defects in CD3D are a cause of severe combined immunodeficiency autosomal recessive T-cell-negative/B-cell-positive/NK-cell-positive (T(-)/B(+)/NK(+) SCID). A form of severe combined immunodeficiency (SCID), a genetically and clinically heterogeneous group of rare congenital disorders characterized by impairment of both humoral and cell-mediated immunity, leukopenia, and low or absent antibody levels. Patients present in infancy recurrent, persistent infections by opportunistic organisms. The common characteristic of all types of SCID is absence of T-cell-mediated cellular immunity due to a defect in T-cell development. |
| Sequence Similarities | Contains 1 ITAM domain. |
Storage & Shipping
| Storage Buffer | pH: 7.20; Preservative: 0.01% Sodium azide; Constituents: 0.05% BSA, 40% Glycerol (glycerin, glycerine), 59% PBS |
|---|---|
| Storage & Shipping | Shipped at 4°C. Store at 4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C. Stable for 12 months at -20°C. |
For research use only. Not for clinical use.
