Anti-CD3D Rabbit Monoclonal Antibody (RMAB-0251429)
Cat. No.: RMAB-0251429
Category: Primary Antibodies
Research Area: Immunology, Stem Cells
INQUIRY
100 μL
Customer Size
Anti-CD3D Rabbit Monoclonal Antibody. Tested in IP, IF, WB applications. This antibody reacts with Human.
Product Features
| Isotype | IgG |
|---|---|
| Clonality | Monoclonal |
| Host Species | Rabbit |
| Form | Liquid |
| Species Reactivity | Human |
| Immunogen | Synthetic peptide. |
| Applications | WB, IP |
Target Information
| Target Symbol | CD3D |
|---|---|
| Target Name | T-cell surface glycoprotein CD3 delta chain |
| UniProt ID | P04234 |
| Function | The CD3 complex mediates signal transduction. |
| Involvement in Disease | Defects in CD3D are a cause of severe combined immunodeficiency autosomal recessive T-cell-negative/B-cell-positive/NK-cell-positive (T(-)/B(+)/NK(+) SCID). A form of severe combined immunodeficiency (SCID), a genetically and clinically heterogeneous group of rare congenital disorders characterized by impairment of both humoral and cell-mediated immunity, leukopenia, and low or absent antibody levels. Patients present in infancy recurrent, persistent infections by opportunistic organisms. The common characteristic of all types of SCID is absence of T-cell-mediated cellular immunity due to a defect in T-cell development. |
| Sequence Similarities | Contains 1 ITAM domain. |
Storage & Shipping
| Storage Buffer | Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles. |
|---|---|
| Storage & Shipping | Dry Ice |
For research use only. Not for clinical use.
