Anti-CD43 Antibody (RMAB-0250360)
Cat. No.: RMAB-0250360
Category: Primary Antibodies
INQUIRY
100 μL
Customer Size
Rabbit monoclonal to CD43
Product Features
Isotype | IgG |
---|---|
Clonality | Monoclonal |
Host Species | Rabbit |
Clone Number | EPR21904 |
Form | Liquid |
Purity | Protein A purified |
Species Reactivity | Human |
Immunogen | Recombinant fragment. |
Applications | WB, IHC-P, ICC/IF, Flow Cyt |
Key Features | Produced recombinantly (animal-free) for high batch-to-batch consistency and long term security of supply; Rabbit monoclonal to CD43; Suitable for: WB, IHC-P, ICC/IF, Flow Cyt; Reacts with: Human |
Target Information
Target Symbol | SPN |
---|---|
Target Name | Deformed epidermal autoregulatory factor 1 homolog |
UniProt ID | P16150 |
Cellular Localization | Membrane. |
Function | One of the major glycoproteins of thymocytes and T lymphocytes. Plays a role in the physicochemical properties of the T-cell surface and in lectin binding. Presents carbohydrate ligands to selectins. Has an extended rodlike structure that could protrude above the glycocalyx of the cell and allow multiple glycan chains to be accessible for binding. Is a counter receptor for SN/Siglec-1 (By similarity). During T-cell activation is actively removed from the T-cell-APC (antigen-presenting cell) contact site thus suggesting a negative regulatory role in adaptive immune response. |
Post-translational Modifications | Glycosylated; has a high content of sialic acid and O-linked carbohydrate structures. |
Storage & Shipping
Storage Buffer | pH: 7.2; Preservative: 0.01% Sodium azide; Constituents: PBS, 50% Glycerol (glycerin, glycerine), 0.05% BSA |
---|---|
Storage & Shipping | Shipped at 4°C. Store at 4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. |
For research use only. Not for clinical use.