Anti-DDX4 / MVH Antibody (RMAB-0250505)
Cat. No.: RMAB-0250505
Category: Primary Antibodies
INQUIRY
100 μg
Customer Size
Rabbit polyclonal to DDX4 / MVH
Product Features
| Isotype | IgG |
|---|---|
| Clonality | Polyclonal |
| Host Species | Rabbit |
| Form | Liquid |
| Purity | Immunogen affinity purified |
| Species Reactivity | Human, Mouse |
| Immunogen | Synthetic peptide within Human DDX4/ MVH aa 7 to the C-terminus (C terminal) conjugated to keyhole limpet haemocyanin. The exact sequence is proprietary. |
| Applications | WB, ICC/IF, IHC-P, IHC-Fr |
| Key Features | Rabbit polyclonal to DDX4 / MVH; Suitable for: WB, ICC/IF, IHC-P, IHC-Fr; Reacts with: Mouse, Human; Isotype: IgG |
Target Information
| Target Symbol | DDX4 |
|---|---|
| Target Name | Probable ATP-dependent RNA helicase DDX4 |
| UniProt ID | Q9NQI0 |
| Cellular Localization | Cytoplasm. Cytoplasm, perinuclear region. Component of the meiotic nuage, also named P granule, a germ-cell-specific organelle required to repress transposon activity during meiosis. |
| Function | Probable ATP-dependent RNA helicase required during spermatogenesis (PubMed:19222, PubMed:21346). Required to repress transposable elements and preventing their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposons. Involved in the secondary piRNAs metabolic process, the production of piRNAs in fetal male germ cells through a ping-pong amplification cycle. |
| Sequence Similarities | Belongs to the DEAD box helicase family. DDX4/VASA subfamily. Contains 1 helicase ATP-binding domain. Contains 1 helicase C-terminal domain. |
Storage & Shipping
| Storage Buffer | pH: 7.40; Preservative: 0.02% Sodium azide; Constituent: PBSBatches of this product that have a concentration < 1mg/ml may have BSA added as a stabilising agent. If you would like information about the formulation of a specific lot, please contact our scientific support team who will be happy to help. |
|---|---|
| Storage & Shipping | Shipped at 4°C. Store at 4°C short term (1-2 weeks). Store at -20°C or -80°C. Avoid freeze / thaw cycle. |
For research use only. Not for clinical use.
