Anti-DDX4 / MVH Antibody (RMAB-0250510)
Cat. No.: RMAB-0250510
Category: Primary Antibodies
INQUIRY
100 μg
Customer Size
Mouse monoclonal to DDX4 / MVH
Product Features
| Isotype | IgG1 |
|---|---|
| Clonality | Monoclonal |
| Host Species | Mouse |
| Clone Number | mWe27591 |
| Form | Liquid |
| Purity | IgG fraction |
| Species Reactivity | Mouse, Human, Common marmoset |
| Immunogen | Synthetic peptide corresponding to Human DDX4/ MVH aa 7 to the C-terminus (C terminal) conjugated to keyhole limpet haemocyanin. |
| Applications | ICC/IF, IHC-P, IHC-Fr, WB |
| Key Features | Mouse monoclonal to DDX4 / MVH; Suitable for: ICC/IF, IHC-P, IHC-Fr, WB; Reacts with: Mouse, Human, Common marmoset; Isotype: IgG1 |
Target Information
| Target Symbol | DDX4 |
|---|---|
| Target Name | Probable ATP-dependent RNA helicase DDX4 |
| UniProt ID | Q9NQI0 |
| Cellular Localization | Cytoplasm. Cytoplasm, perinuclear region. Component of the meiotic nuage, also named P granule, a germ-cell-specific organelle required to repress transposon activity during meiosis. |
| Function | Probable ATP-dependent RNA helicase required during spermatogenesis (PubMed:19222, PubMed:21346). Required to repress transposable elements and preventing their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposons. Involved in the secondary piRNAs metabolic process, the production of piRNAs in fetal male germ cells through a ping-pong amplification cycle. |
| Myeloma | Sp2/-Ag14 |
| Sequence Similarities | Belongs to the DEAD box helicase family. DDX4/VASA subfamily. Contains 1 helicase ATP-binding domain. Contains 1 helicase C-terminal domain. |
Storage & Shipping
| Storage Buffer | pH: 7.40; Preservative: 0.02% Sodium azide; Constituents: PBS, 6.97% L-ArginineSome batches contain 6.97% L-Arginine as a stabilizing agent. For lot-specific buffer information, please contact our Scientific Support team. |
|---|---|
| Storage & Shipping | Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. |
For research use only. Not for clinical use.
