Anti-HDAC6/Histone Deacetylase 6 Rabbit Monoclonal Antibody (RMAB-0251507)
Cat. No.: RMAB-0251507
Category: Primary Antibodies
Research Area: Stem Cells, Epigenetics
INQUIRY
100 μL
Customer Size
Anti-HDAC6/Histone Deacetylase 6 Rabbit Monoclonal Antibody. Tested in IP, IF, IHC, ICC, WB applications. This antibody reacts with Human.
Product Features
| Isotype | IgG |
|---|---|
| Clonality | Monoclonal |
| Host Species | Rabbit |
| Form | Liquid |
| Species Reactivity | Human |
| Immunogen | Synthetic peptide corresponding to Human HDAC6. |
| Applications | WB, IHC |
Target Information
| Target Symbol | HDAC6 |
|---|---|
| Target Name | Histone deacetylase 6 |
| UniProt ID | Q9UBN7 |
| Function | Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes (By similarity). Plays a central role in microtubule-dependent cell motility via deacetylation of tubulin. |
| Post-translational Modifications | Ubiquitinated. Its polyubiquitination however does not lead to its degradation. Sumoylated in vitro. |
| Sequence Similarities | Belongs to the histone deacetylase family. HD type 2 subfamily. Contains 1 UBP-type zinc finger. |
Storage & Shipping
| Storage Buffer | Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles. |
|---|---|
| Storage & Shipping | Dry Ice |
For research use only. Not for clinical use.
