Anti-HES5 Monoclonal Antibody (RMAB-0251435)
Cat. No.: RMAB-0251435
Category: Primary Antibodies
Research Area: Stem Cells, Epigenetics, Neuroscience
INQUIRY
100 μL
Customer Size
Anti-HES5 Monoclonal Antibody. Tested in IP, WB applications. This antibody reacts with Human, Mouse, Rat.
Product Features
| Isotype | IgG |
|---|---|
| Clonality | Monoclonal |
| Host Species | Rabbit |
| Form | Liquid |
| Species Reactivity | Human, Mouse, Rat |
| Immunogen | Recombinant fragment. |
| Applications | WB, IHC |
Target Information
| Target Symbol | HES5 |
|---|---|
| Target Name | Transcription factor HES-5 |
| UniProt ID | Q5TA89 |
| Function | Transcriptional repressor of genes that require a bHLH protein for their transcription. |
| Domain | Has a particular type of basic domain (presence of a helix-interrupting proline) that binds to the N-box (CACNAG), rather than the canonical E-box (CANNTG).The C-terminal WRPW motif is a transcriptional repression domain necessary for the interaction with Groucho/TLE family members, transcriptional corepressors recruited to specific target DNA by Hairy-related proteins. |
| Sequence Similarities | Contains 1 basic helix-loop-helix (bHLH) domain. Contains 1 Orange domain. |
Storage & Shipping
| Storage Buffer | Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles. |
|---|---|
| Storage & Shipping | Dry Ice |
For research use only. Not for clinical use.
