Anti-Human HLA-DR Antibody (RMAB-0251971)
Cat. No.: RMAB-0251971
Category: Primary Antibodies
Research Area: HLA, Immunology, Infectious Diseases, Transplantation Research
INQUIRY
100 μg
Customer Size
The LN3 antibody reacts with the HLA-DR antigen, a major histocompatibility complex (MHC) class II receptor encoded within the human leukocyte antigen (HLA) complex on chromosome 6. HLA-DR is a heterodimeric transmembrane glycoprotein comprising non-covalently associated α (36 kDa) and β (27 kDa) subunits. MHC class II plays a central role in the presentation of antigen-derived peptides to CD4+ T cells, along with CD3/TCR and CD4. HLA-DR is primarily expressed on the surface of antigen-presenting cells, including B cells, dendritic cells, monocytes, macrophages, thymic epithelial cells, and activated T and natural (NK) cells. The LN3 antibody binds to an extracellular epitope that reportedly resides within the HLA-BR1 subunit of HLA-DR.
Product Features
| Isotype | IgG2b, kappa |
|---|---|
| Host Species | Mouse |
| Clone Number | LN3 |
| Conjugate | Alexa Fluor 488, FITC, PE, Unconjugated |
| Species Reactivity | Human, Rhesus |
| Applications | Flow Cyt, Functional Assay, IHC |
| Key Features | Alexa Fluor 488, FITC, PE, Unconjugated |
Target Information
| Target Symbol | HLA-DR |
|---|---|
| Target Name | HLA-DR |
For research use only. Not for clinical use.
