Anti-Human Villin 1 Antibody, Polyclonal (RMAB-0251957)
Cat. No.: RMAB-0251957
Category: Primary Antibodies
Research Area: Organoids
INQUIRY
100 μL
Customer Size
This rabbit polyclonal antibody reacts with human villin 1, a calcium-regulated protein expressed in epithelial cells. Villin 1 is organized into six conserved domains, which make up the villin core, and a C-terminal headpiece domain, which contains an F-actin binding site. Use this polyclonal antibody in applications requiring detection of villin 1, such as western blotting (WB) assays and IHC (IHC). It is verified for use with ICC (ICC).Villin 1 is an important player in the reorganization of microvillar actin filaments and is involved in actin nucleation, polymerization, and severing. It is a key component in the growth and development of intestinal epithelial cells, regulating cell morphology, growth, and apoptosis. Villin 1 has been suggested as a predictive factor in some adenocarcinomas of the endocervix, colon, and lungs. Abnormal villin expression has also been associated with biliary atresia and cholestasis.
Product Features
| Isotype | Not applicable |
|---|---|
| Clonality | Polyclonal |
| Host Species | Rabbit |
| Clone Number | Not applicable |
| Conjugate | Unconjugated |
| Species Reactivity | Human |
| Applications | ICC, IF, IHC, WB |
| Key Features | Unconjugated |
Target Information
| Target Symbol | VIL1 |
|---|---|
| Target Name | Villin1 |
For research use only. Not for clinical use.
