Anti-ICAM1 Antibody (RMAB-0250722)
Cat. No.: RMAB-0250722
Category: Primary Antibodies
INQUIRY
500 μg
Customer Size
Mouse monoclonal to ICAM1
Product Features
| Isotype | IgG1 |
|---|---|
| Clonality | Monoclonal |
| Host Species | Mouse |
| Clone Number | 1A29 |
| Form | Liquid |
| Purity | Protein A purified |
| Species Reactivity | Human, Mouse, Rat |
| Immunogen | Full length protein corresponding to Rat ICAM1. Rat lymph node stroma - Native protein |
| Applications | ICC, WB, IHC-P, Flow Cyt |
| Key Features | Mouse monoclonal to ICAM1; Suitable for: ICC, WB, IHC-P, Flow Cyt; Reacts with: Mouse, Rat, Human; Isotype: IgG1 |
Target Information
| Target Symbol | ICAM1 |
|---|---|
| Target Name | Intercellular adhesion molecule 1 |
| UniProt ID | P05362 |
| Cellular Localization | Membrane. |
| Function | ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). During leukocyte trans-endothelial migration, ICAM1 engagement promotes the assembly of endothelial apical cups through ARHGEF26/SGEF and RHOG activation. In case of rhinovirus infection acts as a cellular receptor for the virus. |
| Post-translational Modifications | Monoubiquitinated, which is promoted by MARCH9 and leads to endocytosis. |
| Sequence Similarities | Belongs to the immunoglobulin superfamily. ICAM family. Contains 5 Ig-like C2-type (immunoglobulin-like) domains. |
Storage & Shipping
| Storage Buffer | Constituent: 100% PBS. Preservative negative and carrier free. |
|---|---|
| Storage & Shipping | Shipped at 4°C. Store at 4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. |
For research use only. Not for clinical use.
