Anti-ICAM1 Antibody (RMAB-0250727)
Cat. No.: RMAB-0250727
Category: Primary Antibodies
INQUIRY
100 μL
Customer Size
Rabbit monoclonal to ICAM1
Product Features
| Isotype | IgG |
|---|---|
| Clonality | Monoclonal |
| Host Species | Rabbit |
| Clone Number | EPR24639-3 |
| Form | Liquid |
| Purity | Protein A purified |
| Species Reactivity | Human, Rat |
| Immunogen | Recombinant fragment. |
| Applications | Flow Cyt, IP, IHC-P, ICC/IF, WB |
| Key Features | Produced recombinantly (animal-free) for high batch-to-batch consistency and long term security of supply; Rabbit monoclonal to ICAM1; Suitable for: Flow Cyt, IP, IHC-P, ICC/IF, WB; Knockout validated; Reacts with: Rat, Human |
Target Information
| Target Symbol | ICAM1 |
|---|---|
| Target Name | Intercellular adhesion molecule 1 |
| UniProt ID | P05362 |
| Cellular Localization | Membrane. |
| Function | ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). During leukocyte trans-endothelial migration, ICAM1 engagement promotes the assembly of endothelial apical cups through ARHGEF26/SGEF and RHOG activation. In case of rhinovirus infection acts as a cellular receptor for the virus. |
| Post-translational Modifications | Monoubiquitinated, which is promoted by MARCH9 and leads to endocytosis. |
| Sequence Similarities | Belongs to the immunoglobulin superfamily. ICAM family. Contains 5 Ig-like C2-type (immunoglobulin-like) domains. |
Storage & Shipping
| Storage Buffer | pH: 7.2; Preservative: 0.01% Sodium azide; Constituents: 59.94% PBS, 40% Glycerol (glycerin, glycerine), 0.05% BSA |
|---|---|
| Storage & Shipping | Shipped at 4°C. Store at 4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C. Avoid freeze / thaw cycle. |
For research use only. Not for clinical use.
