Anti-ICAM1/Cd54 Rabbit Monoclonal Antibody (RMAB-0251472)
Cat. No.: RMAB-0251472
Category: Primary Antibodies
Research Area: Cardiovascular, Inflammation & Arthritis, Immunology, Stem Cells
INQUIRY
100 μL
Customer Size
Anti-ICAM1/Cd54 Rabbit Monoclonal Antibody. Tested in Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human.
Product Features
| Isotype | IgG |
|---|---|
| Clonality | Monoclonal |
| Host Species | Rabbit |
| Form | Liquid |
| Species Reactivity | Human |
| Immunogen | Full length protein corresponding to Rat ICAM1. Rat lymph node stroma - Native protein |
| Applications | WB |
Target Information
| Target Symbol | ICAM1 |
|---|---|
| Target Name | Intercellular adhesion molecule 1 |
| UniProt ID | P05362 |
| Function | ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). During leukocyte trans-endothelial migration, ICAM1 engagement promotes the assembly of endothelial apical cups through ARHGEF26/SGEF and RHOG activation. In case of rhinovirus infection acts as a cellular receptor for the virus. |
| Post-translational Modifications | Monoubiquitinated, which is promoted by MARCH9 and leads to endocytosis. |
| Sequence Similarities | Belongs to the immunoglobulin superfamily. ICAM family. Contains 5 Ig-like C2-type (immunoglobulin-like) domains. |
Storage & Shipping
| Storage Buffer | Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles. |
|---|---|
| Storage & Shipping | Dry Ice |
For research use only. Not for clinical use.
