Anti-IFITM1 Antibody (RMAB-0250736)
Cat. No.: RMAB-0250736
Category: Primary Antibodies
INQUIRY
100 μL
Customer Size
Rabbit monoclonal to IFITM1
Product Features
| Isotype | IgG |
|---|---|
| Clonality | Monoclonal |
| Host Species | Rabbit |
| Clone Number | EPR22620-12 |
| Form | Liquid |
| Purity | Protein A purified |
| Species Reactivity | Human |
| Immunogen | Synthetic peptide. |
| Applications | Flow Cyt (Intra), WB, ICC/IF, IP, IHC-P |
| Key Features | Produced recombinantly (animal-free) for high batch-to-batch consistency and long term security of supply; Rabbit monoclonal to IFITM1; Suitable for: Flow Cyt (Intra), WB, ICC/IF, IP, IHC-P; Reacts with: Human |
Target Information
| Target Symbol | IFITM1 |
|---|---|
| Target Name | Interferon-induced transmembrane protein 1 |
| UniProt ID | P13164 |
| Cellular Localization | Cell membrane. |
| Function | IFN-induced antiviral protein that mediate cellular innate immunity to at least three major human pathogens, namely influenza A H1N1 virus, West Nile virus, and dengue virus by inhibiting the early step(s) of replication. Plays a key role in the antiproliferative action of IFN-gamma either by inhibiting the ERK activition or by arresting cell growth in G1 phase in a p53-dependent manner. Implicated in the control of cell growth. Component of a multimeric complex involved in the transduction of antiproliferative and homotypic adhesion signals. |
| Post-translational Modifications | Palmitoylation on membrane-proximal cysteines controls clustering in membrane compartments and antiviral activity against influenza virus. |
| Sequence Similarities | Belongs to the CD225 family. |
Storage & Shipping
| Storage Buffer | pH: 7.2; Preservative: 0.01% Sodium azide; Constituents: 40% Glycerol, 0.05% BSA, PBS |
|---|---|
| Storage & Shipping | Shipped at 4°C. Store at 4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. |
For research use only. Not for clinical use.
