Anti-MAP2 Antibody - Mouse IgG2a (Chimeric) (RMAB-0250843)
Cat. No.: RMAB-0250843
Category: Primary Antibodies
INQUIRY
100 μL
10 µL
Mouse monoclonal to MAP2 - Chimeric
Product Features
| Isotype | IgG2a |
|---|---|
| Clonality | Monoclonal |
| Host Species | Mouse |
| Clone Number | EPR19691 |
| Form | Liquid |
| Purity | Protein A purified |
| Species Reactivity | Human, Mouse, Rat |
| Immunogen | Recombinant fragment. |
| Applications | IHC-Fr, IHC-P, ICC/IF |
| Key Features | Produced recombinantly (animal-free) for high batch-to-batch consistency and long term security of supply; Mouse monoclonal to MAP2 - Chimeric; Suitable for: IHC-Fr, IHC-P, ICC/IF; Reacts with: Mouse, Rat, Human |
Target Information
| Target Symbol | MAP2 |
|---|---|
| Target Name | Microtubule-associated protein 2 |
| UniProt ID | P11137 |
| Cellular Localization | Cytoplasm, cytoskeleton. |
| Function | The exact function of MAP2 is unknown but MAPs may stabilize the microtubules against depolymerization. They also seem to have a stiffening effect on microtubules. |
| Post-translational Modifications | Phosphorylated at serine residues in K-X-G-S motifs by MAP/microtubule affinity-regulating kinase (MARK1 or MARK2), causing detachment from microtubules, and their disassembly (By similarity). Isoform 2 is probably phosphorylated by PKA at Ser-323, Ser-354 and Ser-386 and by FYN at Tyr-67. |
| Sequence Similarities | Contains 3 Tau/MAP repeats. |
Storage & Shipping
| Storage Buffer | pH: 7.20; Preservative: 0.01% Sodium azide; Constituents: 59% PBS, 40% Glycerol (glycerin, glycerine), 0.05% BSA |
|---|---|
| Storage & Shipping | Shipped at 4°C. Store at 4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. |
For research use only. Not for clinical use.
