Anti-MELK Antibody (RMAB-0250856)
Cat. No.: RMAB-0250856
Category: Primary Antibodies
INQUIRY
100 μL
Customer Size
Rabbit monoclonal to MELK
Product Features
| Isotype | IgG |
|---|---|
| Clonality | Monoclonal |
| Host Species | Rabbit |
| Clone Number | EPR3981 |
| Form | Liquid |
| Purity | Protein A purified |
| Species Reactivity | Human |
| Immunogen | Synthetic peptide. |
| Applications | WB |
| Key Features | Produced recombinantly (animal-free) for high batch-to-batch consistency and long term security of supply; Rabbit monoclonal to MELK; Suitable for: WB; Knockout validated; Reacts with: Human |
Target Information
| Target Symbol | MELK |
|---|---|
| Target Name | Maternal embryonic leucine zipper kinase |
| UniProt ID | Q14680 |
| Cellular Localization | Cytoplasm. |
| Function | Phosphorylates ZNF622 and may contribute to its redirection to the nucleus. May be involved in the inhibition of spliceosome assembly during mitosis. |
| Post-translational Modifications | Autophosphorylated. Thr-478 phosphorylation during mitosis promotes interaction with PPP1R8. |
| Sequence Similarities | Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. SNF1 subfamily. Contains 1 KA1 (kinase-associated) domain. Contains 1 protein kinase domain. |
Storage & Shipping
| Storage Buffer | pH: 7.20; Preservative: 0.05% Sodium azide; Constituents: 40% Glycerol (glycerin, glycerine), 9.85% Tris glycine, 50% Tissue culture supernatant |
|---|---|
| Storage & Shipping | Shipped at 4°C. Store at 4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C. Stable for 12 months at -20°C. |
For research use only. Not for clinical use.
