Anti-p75 NGF Receptor Antibody (RMAB-0250949)
Cat. No.: RMAB-0250949
Category: Primary Antibodies
INQUIRY
100 μg
Customer Size
Rat monoclonal to p75 NGF Receptor
Product Features
| Isotype | IgG2a |
|---|---|
| Clonality | Monoclonal |
| Host Species | Rat |
| Clone Number | NORI146C |
| Form | Liquid |
| Purity | Protein A purified |
| Species Reactivity | Mouse |
| Immunogen | Recombinant fragment. |
| Applications | IHC-P, WB, IHC-Fr |
| Key Features | Produced recombinantly (animal-free) for high batch-to-batch consistency and long term security of supply; Rat monoclonal to p75 NGF Receptor; Suitable for: IHC-P, WB, IHC-Fr; Reacts with: Mouse |
Target Information
| Target Symbol | NGFR |
|---|---|
| Target Name | Tumor necrosis factor receptor superfamily member 16 |
| UniProt ID | P08138 |
| Cellular Localization | Membrane. |
| Function | Low affinity receptor which can bind to NGF, BDNF, NT-3, and NT-4. Can mediate cell survival as well as cell death of neural cells. |
| Post-translational Modifications | N- and O-glycosylated. O-linked glycans consist of Gal(1-3)GalNAc core elongated by 1 or 2 NeuNAc. Phosphorylated on serine residues. |
| Domain | Death domain is responsible for interaction with RANBP9.The extracellular domain is responsible for interaction with NTRK1. |
| Sequence Similarities | Contains 1 death domain. Contains 4 TNFR-Cys repeats. |
Storage & Shipping
| Storage Buffer | pH: 7.2; Preservative: 0.01% Sodium azide; Constituents: PBS, 0.05% BSA, 40% Glycerol (glycerin, glycerine) |
|---|---|
| Storage & Shipping | Shipped at 4°C. Store at 4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. |
For research use only. Not for clinical use.
