Anti-PCSK9/Proprotein Convertase 9 Rabbit Monoclonal Antibody (RMAB-0251337)
Cat. No.: RMAB-0251337
Category: Primary Antibodies
Research Area: Cardiovascular, Cancer Research, Stem Cells, Metabolism
INQUIRY
100 μL
Customer Size
Anti-PCSK9/Proprotein Convertase 9 Rabbit Monoclonal Antibody. Tested in IP, WB applications. This antibody reacts with Human.
Product Features
| Isotype | IgG |
|---|---|
| Clonality | Monoclonal |
| Host Species | Rabbit |
| Form | Liquid |
| Species Reactivity | Human |
| Immunogen | Recombinant fragment. |
| Applications | WB, IHC |
Target Information
| Target Symbol | PCSK9 |
|---|---|
| Target Name | Proprotein convertase subtilisin/kexin type 9 |
| UniProt ID | Q8NBP7 |
| Function | May be implicated in the differentiation of cortical neurons and may play a role in cholesterol homeostasis. |
| Involvement in Disease | Defects in PCSK9 are the cause of familial hypercholesterolemia 3 (FH3). FH3 inheritance is autosomal dominant. |
| Post-translational Modifications | The soluble zymogen undergoes autocatalytic intramolecular processing in the endoplasmic reticulum, resulting in the cleavage of its propeptide that remains associated with the secreted enzyme. |
| Sequence Similarities | Belongs to the peptidase S8 family. Contains 1 peptidase S8 domain. |
Storage & Shipping
| Storage Buffer | Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles. |
|---|---|
| Storage & Shipping | Dry Ice |
For research use only. Not for clinical use.
