Anti-ROR2 Antibody (RMAB-0251006)
Cat. No.: RMAB-0251006
Category: Primary Antibodies
INQUIRY
100 μL
10 µL
Rabbit monoclonal to ROR2
Product Features
| Isotype | IgG |
|---|---|
| Clonality | Monoclonal |
| Host Species | Rabbit |
| Clone Number | EPR27134-21 |
| Form | Liquid |
| Purity | Protein A purified |
| Species Reactivity | Human, Mouse |
| Immunogen | Synthetic peptide. |
| Applications | WB |
| Key Features | Produced recombinantly (animal-free) for high batch-to-batch consistency and long term security of supply; Rabbit monoclonal to ROR2; Suitable for: WB; Knockout validated; Reacts with: Mouse, Human |
Target Information
| Target Symbol | ROR2 |
|---|---|
| Target Name | Tyrosine-protein kinase transmembrane receptor ROR2 |
| UniProt ID | Q01974 |
| Cellular Localization | Cell membrane. |
| Developmental Stage | Expressed at high levels during early embryonic development. The expression levels drop strongly around day 16 and there are only very low levels in adult tissues. |
| Function | Tyrosine-protein kinase receptor which may be involved in the early formation of the chondrocytes. It seems to be required for cartilage and growth plate development. Phosphorylates YWHAB, leading to induction of osteogenesis and bone formation. |
| Involvement in Disease | Brachydactyly B1Robinow syndrome autosomal recessive |
| Sequence Similarities | Belongs to the protein kinase superfamily. Tyr protein kinase family. ROR subfamily. Contains 1 FZ (frizzled) domain. Contains 1 Ig-like C2-type (immunoglobulin-like) domain. Contains 1 kringle domain. Contains 1 protein kinase domain. |
Storage & Shipping
| Storage Buffer | pH: 7.2; Preservative: 0.01% Sodium azide; Constituents: 59% PBS, 0.05% BSA, 40% Glycerol (glycerin, glycerine) |
|---|---|
| Storage & Shipping | Shipped at 4°C. Store at 4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. |
For research use only. Not for clinical use.
