Anti-Sall4 Antibody (RMAB-0251023)
Cat. No.: RMAB-0251023
Category: Primary Antibodies
INQUIRY
100 μL
1 mL
Rabbit monoclonal to Sall4
Product Features
| Isotype | IgG |
|---|---|
| Clonality | Monoclonal |
| Host Species | Rabbit |
| Clone Number | SP289 |
| Form | Liquid |
| Purity | Protein A purified |
| Species Reactivity | Human |
| Immunogen | Synthetic peptide. |
| Applications | IHC-P, Flow Cyt (Intra), ICC/IF |
| Key Features | Produced recombinantly (animal-free) for high batch-to-batch consistency and long term security of supply; Rabbit monoclonal to Sall4; Suitable for: IHC-P, Flow Cyt (Intra), ICC/IF; Reacts with: Human |
Target Information
| Target Symbol | SALL4 |
|---|---|
| Target Name | Sal-like protein 4 |
| UniProt ID | Q9UJQ4 |
| Cellular Localization | Nucleus. |
| Function | Probable transcription factor. |
| Involvement in Disease | Defects in SALL4 are the cause of Duane-radial ray syndrome (DRRS); also known as Okihiro syndrome. DRRS is a disorder characterized by the association of forearm malformations with Duane retraction syndrome.Defects in SALL4 are the cause of oculootoradial syndrome (OORS). Oculootoradial syndrome is an autosomal dominant condition characterized by upper limbs anomalies (radial ray defects, carpal bones fusion), extraocular motor disturbances, congenital bilateral non-progressive mixed hearing loss. Other less consistent malformations include heart involvement, mild thrombocytopenia and leukocytosis (before age 5), shoulder girdle hypoplasia, imperforate anus, kidney malrotation or rectovaginal fistula. The IVIC syndrome is an allelic disorder of Duane-radial ray syndrome (DRRS) with a similar phenotype. |
| Sequence Similarities | Belongs to the sal C2H2-type zinc-finger protein family. Contains 7 C2H2-type zinc fingers. |
Storage & Shipping
| Storage Buffer | pH: 7.20; Preservative: 0.1% Sodium azide; Constituents: 1% BSA, PBS |
|---|---|
| Storage & Shipping | Shipped at 4°C. Store at 4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. |
For research use only. Not for clinical use.
