Anti-SLAM / CD150 Antibody (RMAB-0251033)
Cat. No.: RMAB-0251033
Category: Primary Antibodies
INQUIRY
100 μL
Customer Size
Rabbit monoclonal to SLAM / CD150
Product Features
| Isotype | IgG |
|---|---|
| Clonality | Monoclonal |
| Host Species | Rabbit |
| Clone Number | EPR22904-135 |
| Form | Liquid |
| Purity | Protein A purified |
| Species Reactivity | Mouse, Rat |
| Immunogen | Recombinant fragment. |
| Applications | WB, IHC-P |
| Key Features | Produced recombinantly (animal-free) for high batch-to-batch consistency and long term security of supply; Rabbit monoclonal to SLAM / CD150; Suitable for: WB, IHC-P; Reacts with: Mouse, Rat |
Target Information
| Target Symbol | SLAMF1 |
|---|---|
| Target Name | Signaling lymphocytic activation molecule |
| UniProt ID | Q13291 |
| Cellular Localization | Cell membrane. Present on the surface of B-cells and T-cells. |
| Function | High-affinity self-ligand important in bidirectional T-cell to B-cell stimulation. SLAM-induced signal-transduction events in T-lymphocytes are different from those in B-cells. Two modes of SLAM signaling are likely to exist: one in which the inhibitor SH2D1A acts as a negative regulator and another in which protein-tyrosine phosphatase 2C (PTPN11)-dependent signal transduction operates. |
| Post-translational Modifications | Phosphorylated by FYN. |
| Domain | The most membrane-proximal SH2-binding motif interacts with SH2 domain of SH2D1A and does not need to be phosphorylated on tyrosine residues. |
| Sequence Similarities | Contains 1 Ig-like C2-type (immunoglobulin-like) domain. Contains 1 Ig-like V-type (immunoglobulin-like) domain. |
Storage & Shipping
| Storage Buffer | pH: 7.2; Preservative: 0.01% Sodium azide; Constituents: PBS, 0.05% BSA, 40% Glycerol (glycerin, glycerine) |
|---|---|
| Storage & Shipping | Shipped at 4°C. Store at 4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. |
For research use only. Not for clinical use.
