Anti-SPARC Antibody (RMAB-0251107)
Cat. No.: RMAB-0251107
Category: Primary Antibodies
INQUIRY
1 mL
500 μL
Rabbit monoclonal to SPARC
Product Features
| Isotype | IgG |
|---|---|
| Clonality | Monoclonal |
| Host Species | Rabbit |
| Clone Number | SP205 |
| Form | Liquid |
| Purity | Protein A/G purified |
| Species Reactivity | Human |
| Immunogen | Synthetic peptide. |
| Applications | WB, IHC-P, ICC/IF, Flow Cyt (Intra) |
| Key Features | Produced recombinantly (animal-free) for high batch-to-batch consistency and long term security of supply; Rabbit monoclonal to SPARC; Suitable for: WB, IHC-P, ICC/IF, Flow Cyt (Intra); Reacts with: Human |
Target Information
| Target Symbol | SPARC |
|---|---|
| Target Name | SPARC |
| UniProt ID | P09486 |
| Cellular Localization | Secreted > extracellular space > extracellular matrix > basement membrane. In or around the basement membrane. |
| Developmental Stage | Expressed at high levels in tissues undergoing morphogenesis, remodeling and wound repair. |
| Function | Appears to regulate cell growth through interactions with the extracellular matrix and cytokines. Binds calcium and copper, several types of collagen, albumin, thrombospondin, PDGF and cell membranes. There are two calcium binding sites; an acidic domain that binds 5 to 8 Ca(2+) with a low affinity and an EF-hand loop that binds a Ca(2+) ion with a high affinity. |
| Sequence Similarities | Belongs to the SPARC family. Contains 1 EF-hand domain. Contains 1 follistatin-like domain. Contains 1 Kazal-like domain. |
Storage & Shipping
| Storage Buffer | pH: 7.60; Preservative: 0.1% Sodium azide; Constituents: PBS, 1% BSA |
|---|---|
| Storage & Shipping | Shipped at 4°C. Store at 4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. |
For research use only. Not for clinical use.
