Anti-VCAM1 Antibody (RMAB-0251179)
Cat. No.: RMAB-0251179
Category: Primary Antibodies
INQUIRY
100 μL
Customer Size
Rabbit monoclonal to VCAM1
Product Features
| Isotype | IgG |
|---|---|
| Clonality | Monoclonal |
| Host Species | Rabbit |
| Clone Number | EPR5047 |
| Form | Liquid |
| Purity | Protein A purified |
| Species Reactivity | Human, Mouse, Rat |
| Immunogen | Synthetic peptide. |
| Applications | WB, IP, IHC-P, Flow Cyt (Intra), ICC/IF, Indirect ELISA |
| Key Features | Produced recombinantly (animal-free) for high batch-to-batch consistency and long term security of supply; Rabbit monoclonal to VCAM1; Suitable for: WB, IP, IHC-P, Flow Cyt (Intra), ICC/IF, Indirect ELISA; Knockout validated; Reacts with: Mouse, Rat, Human |
Target Information
| Target Symbol | VCAM1 |
|---|---|
| Target Name | Vascular cell adhesion protein 1 |
| UniProt ID | P19320 |
| Cellular Localization | Membrane. |
| Function | Important in cell-cell recognition. Appears to function in leukocyte-endothelial cell adhesion. Interacts with the beta-1 integrin VLA4 on leukocytes, and mediates both adhesion and signal transduction. The VCAM1/VLA4 interaction may play a pathophysiologic role both in immune responses and in leukocyte emigration to sites of inflammation. |
| Post-translational Modifications | Sialoglycoprotein. |
| Domain | Either the first or the fourth Ig-like C2-type domain is required for VLA4-dependent cell adhesion. |
| Sequence Similarities | Contains 7 Ig-like C2-type (immunoglobulin-like) domains. |
Storage & Shipping
| Storage Buffer | pH: 7.2; Preservative: 0.01% Sodium azide; Constituents: 40% Glycerol, 0.05% BSA, 59% PBS |
|---|---|
| Storage & Shipping | Shipped at 4°C. Store at 4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C. Stable for 12 months at -20°C. |
For research use only. Not for clinical use.
