Anti-Wnt7a Antibody - BSA and Azide free (Detector) (RMAB-0252043)
Cat. No.: RMAB-0252043
Category: Antibody Pair
INQUIRY
100 μg
1 mg
Rabbit monoclonal to Wnt7a - BSA and Azide free (Detector)
Product Features
| Isotype | IgG |
|---|---|
| Clonality | Monoclonal |
| Host Species | Rabbit |
| Clone Number | EPR23471-215 |
| Form | Liquid |
| Species Reactivity | Mouse, Rat, Human |
| Applications | Sandwich ELISA |
| Key Features | Produced recombinantly (animal-free) for high batch-to-batch consistency and long term security of supply; Rabbit monoclonal to Wnt7a - BSA and Azide free (Detector); Suitable for: Sandwich ELISA; Reacts with: Mouse, Rat, Human |
Target Information
| Target Symbol | WNT7A |
|---|---|
| Target Name | Protein Wnt-7a |
| UniProt ID | O00755 |
| Cellular Localization | Secreted > extracellular space > extracellular matrix. |
| Function | Ligand for members of the frizzled family of seven transmembrane receptors. Probable developmental protein. Signaling by Wnt-7a allows sexually dimorphic development of the mullerian ducts. |
| Involvement in Disease | Defects in WNT7A are the cause of limb/pelvis-hypoplasia/aplasia syndrome (LPHAS); also known asof ulna and fibula with severe limb deficiency. LPHAS is a limb-malformation disorder characterized by various degrees of limb aplasia/hypoplasia and joint dysplasia.Defects in WNT7A are a cause of Fuhrmann syndrome (FUHRS); also known as fibular aplasia or hypoplasia femoral bowing and poly- syn- and oligodactyly. Fuhrmann syndrome is a distinct limb-malformation disorder characterized also by various degrees of limb aplasia/hypoplasia and joint dysplasia. |
| Sequence Similarities | Belongs to the Wnt family. |
Storage & Shipping
| Storage Buffer | Constituent: 100% PBS |
|---|---|
| Storage & Shipping | Shipped at 4°C. Store at 4°C. |
For research use only. Not for clinical use.
