BIO (RMML-00120129)
Cat. No.: RMML-00120129
Category: Inhibitors & Activators
INQUIRY
1 mg
5 mg
BIO is an indirubin compound that is cell-permeable and is a selective and potent reversible inhibitor of GSK3α and GSK3β. Maintains self-renewal of mouse embryonic stem. Maintains self-renewal of human ES cells in unconditioned medium throμgh a SMAD 2/3 dependent mechanism. Induces proliferation of neonatal and adult rat cardiomyocytes. Promotes differentiation of cardiomyocytes from human ES and iPS cells.
Product Features
| Purity | ≥ 98% |
|---|---|
| Applications | Differentiation, Expansion, Maintenance, Reprogramming |
| Cross Reactivity | Human, Mouse, Non-Human Primate, Other, Rat |
Compound Information
| Target Pathways | WNT |
|---|---|
| CAS Number | 667463-62-9 |
| Molecular Formula | C₁₆H₁₀BrN₃O₂ |
Storage & Shipping
| Handling | Refer to SDS for further information. |
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For research use only. Not for clinical use.