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BIO (RMML-00120129)

Cat. No.: RMML-00120129

Category: Inhibitors & Activators

INQUIRY 1 mg 5 mg
BIO is an indirubin compound that is cell-permeable and is a selective and potent reversible inhibitor of GSK3α and GSK3β. Maintains self-renewal of mouse embryonic stem. Maintains self-renewal of human ES cells in unconditioned medium throμgh a SMAD 2/3 dependent mechanism. Induces proliferation of neonatal and adult rat cardiomyocytes. Promotes differentiation of cardiomyocytes from human ES and iPS cells.

Product Features

Purity ≥ 98%
Applications Differentiation, Expansion, Maintenance, Reprogramming
Cross Reactivity Human, Mouse, Non-Human Primate, Other, Rat

Compound Information

Target Pathways WNT
CAS Number 667463-62-9
Molecular Formula C₁₆H₁₀BrN₃O₂

Storage & Shipping

Handling Refer to SDS for further information.

For research use only. Not for clinical use.