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Bovine Fibronectin Leucine Rich Transmembrane Protein 2 ELISA Kit

Bovine Fibronectin Leucine Rich Transmembrane Protein 2 ELISA Kit (RMEK-0150210)

Cat. No.: RMEK-0150210

Category: ELISA Kits

INQUIRY 1 x 96 tests
This ELISA kit is a 1. 5 hour solid-phase ELISA designed for the quantitative determination of the targets. This ELISA kit for research use only, not for therapeutic or diagnostic applications!

Product Features

Species Reactivity Bovine
Assay Time 1.5 h

Target Information

Target Symbol FLRT2
UniProt ID O43155
Biomarker of SCs/CSCs Non Small Cell Lung Cancer
Function Functions in cell-cell adhesion, cell migration and axon guidance. Mediates cell-cell adhesion via its interactions with ADGRL3 and probably also other latrophilins that are expressed at the surface of adjacent cells. May play a role in the migration of cortical neurons during brain development via its interaction with UNC5D. Mediates axon growth cone collapse and plays a repulsive role in neuron guidance via its interaction with UNC5D, and possibly also other UNC-5 family members. Plays a role in fibroblast growth factor-mediated signaling cascades. Required for normal organization of the cardiac basement membrane during embryogenesis, and for normal embryonic epicardium and heart morphogenesis.
Cellular Localization Cell membrane; Single-pass membrane protein. Endoplasmic reticulum membrane. Cell junction, focal adhesion. Secreted, extracellular space, extracellular matrix. Microsome membrane. Secreted. Synapse, synaptosome. Proteolytic cleavage gives rise to a shedded ectodomain.
Post-transcriptional Modifications N-glycosylated. Proteolytic cleavage in the juxtamembrane region gives rise to a soluble ectodomain. Cleavage is probably effected by a metalloprotease.

Storage & Shipping

Storage Store at 2-8°C
Shipping Gel Packs
Stability The stability of kit is determined by the loss rate of activity. The loss rate of this kit is less than 5% within the expiration date under appropriate storage condition.

For research use only. Not for clinical use.