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CD 437, RARgamma-selective agonist. (RMML-00120779)

Cat. No.: RMML-00120779

Category: Inhibitors & Activators

INQUIRY 50 mg 10 mg
Potent, cell-permeable RARγ-selective agonist.

Product Features

Source Synthetic
Purity > 99%
Key Features Potent, cell-permeable RARγ-selective agonist.; CAS Number: 125316-60-1; Purity: > 99%; Soluble in DMSO to 100 mM and in ethanol to 10 mM; Form / State: Solid; Source: Synthetic

Compound Information

Target Pathways RARgamma-selective
Biological Description Potent, cell-permeable RARγ-selective agonist (EC50 values are 140, 28 and 7 nM for RAR-α, β and γ respectively). Shows RARγ-dependent and -independent effects on differentiation and apoptosis. Shows antitumor effects in vivo.
CAS Number 125316-60-1
Chemical Name 6-(4-Hydroxy-3-tricyclo[3.3.1.13,7]dec-1-ylphenyl)-2-naphthalenecarboxylic acid
SMILES O=C(O)c1ccc2cc(ccc2c1)c6cc(C5C3CC4CC5CC(C3)C4)c(O)cc6
Molecular Formula C27H26O3
Molecular Weight 398.50 Da
PubChem Identifier 135411

Storage & Shipping

Handling Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Toxic, refer to SDS for further information.
Solubility Soluble in DMSO to 100 mM and in ethanol to 10 mM
Storage & Shipping Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months.

For research use only. Not for clinical use.