EX527 (RMML-00120260)
Cat. No.: RMML-00120260
Category: Inhibitors & Activators
INQUIRY
1 mg
5 mg
EX527 is a cell-permeable, selective inhibitor of mammalian sirtuin 1. SIRT1 is a nicotinamide adenine dinucleotide. Increases the production of oligodendrocytes from differentiating neural stem cells and neural progenitor cells in vitro. Restores the microvascular response during the hypoinflammatory phase in a mouse model of sepsis, and enhances the systemic innate immune response. Delays cyst growth in kidneys of PKD1 knockout mouse models
Product Features
| Purity | ≥ 98% |
|---|---|
| Applications | Differentiation |
| Cross Reactivity | Human, Mouse, Non-Human Primate, Other, Rat |
Compound Information
| Target Pathways | Epigenetic |
|---|---|
| Alternative Names | Selisistat |
| CAS Number | 49843-98-3 |
| Molecular Formula | C₁₃H₁₃ClN₂O |
| Molecular Weight | 248.7 Da |
Storage & Shipping
| Handling | Refer to SDS for further information. |
|---|
For research use only. Not for clinical use.
