Guinea Pig B cell CLL/lymphoma 9 Protein(BCL9) ELISA Kit (RMEK-0151912)
Cat. No.: RMEK-0151912
Category: ELISA Kits
INQUIRY
1 x 96 tests
This ELISA kit is a 1. 5 hour solid-phase ELISA designed for the quantitative determination of the targets. This ELISA kit for research use only, not for therapeutic or diagnostic applications!
Product Features
| Species Reactivity | Guinea Pig |
|---|---|
| Assay Time | 1.5 h |
Target Information
| Target Symbol | BCL9 |
|---|---|
| UniProt ID | O00512 |
| Biomarker of SCs/CSCs | Non Small Cell Lung Cancer |
| Function | Involved in signal transduction through the Wnt pathway. Promotes beta-catenin's transcriptional activity (By similarity). |
| Cellular Localization | Nucleus. |
| Involvement in Disease | A chromosomal aberration involving BCL9 is found in a patient with precursor B-cell acute lymphoblastic leukemia (ALL). Translocation t(1; 14)(q21; q32). This translocation leaves the coding region intact, but may have pathogenic effects due to alterations in the expression level of BCL9. Several cases of translocations within the 3'-UTR of BCL9 have been found in B-cell malignancies. |
Storage & Shipping
| Storage | Store at 2-8°C |
|---|---|
| Shipping | Gel Packs |
| Stability | The stability of kit is determined by the loss rate of activity. The loss rate of this kit is less than 5% within the expiration date under appropriate storage condition. |
For research use only. Not for clinical use.
