Guinea Pig Secreted Frizzled Related Protein 4 ELISA Kit (RMEK-0152215)
Cat. No.: RMEK-0152215
Category: ELISA Kits
INQUIRY
1 x 96 tests
This ELISA kit is a 1. 53 hour solid-phase ELISA designed for the quantitative determination of the targets. This ELISA kit for research use only, not for therapeutic or diagnostic applications!
Product Features
| Species Reactivity | Guinea Pig |
|---|---|
| Assay Time | 1.53 h |
Target Information
| Target Symbol | SFRP4 |
|---|---|
| UniProt ID | Q6FHJ7 |
| Biomarker of SCs/CSCs | Non Small Cell Lung Cancer |
| Function | Soluble frizzled-related proteins (sFRPS) function as modulators of Wnt signaling through direct interaction with Wnts. They have a role in regulating cell growth and differentiation in specific cell types (By similarity). SFRP4 plays a role in bone morphogenesis. May also act as a regulator of adult uterine morphology and function. May also increase apoptosis during ovulation possibly through modulation of FZ1/FZ4/WNT4 signaling (By similarity). Has phosphaturic effects by specifically inhibiting sodium-dependent phosphate uptake. |
| Cellular Localization | Secreted. Cytoplasmic in ovarian tumor cells. |
| Domain | The FZ domain is involved in binding with Wnt ligands. |
| Involvement in Disease | Pyle disease (PYL): A disorder characterized by cortical-bone thinning, limb deformity, bone fragility and fractures. The disease is caused by variants affecting the gene represented in this entry. |
Storage & Shipping
| Storage | Store at 2-8°C |
|---|---|
| Shipping | Gel Packs |
| Stability | The stability of kit is determined by the loss rate of activity. The loss rate of this kit is less than 5% within the expiration date under appropriate storage condition. |
For research use only. Not for clinical use.
