Human Albumin Matched Antibody Pair Kit (RMAB-0252021)
Cat. No.: RMAB-0252021
Category: Antibody Pair
INQUIRY
5 x 96 tests
Human Albumin Matched Antibody Pair Kits include a capture and a biotinylated detector antibody pair, along with a calibrated protein standard, suitable for sandwich ELISA. The Matched Antibody Pair Kit can be used to quantify native and recombinant human Albumin._x000D_
Product Features
| Species Reactivity | Human |
|---|---|
| Range | 625 pg/mL - 40000 pg/mL |
| Sensitivity | 453 pg/mL |
| Applications | ELISA |
| Key Features | Unlabeled capture antibody, biotin-labeled detection antibody and calibrated protein standard; For economical ELISA and ELISA-based assay development; Reacts with: Human; Range: 625 pg/mL - 40000 pg/mL |
Target Information
| Target Symbol | ALB |
|---|---|
| Target Name | Albumin |
| UniProt ID | P02768 |
| Cellular Localization | Secreted. |
| Function | Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds% of all plasma zinc. |
| Involvement in Disease | Defects in ALB are a cause of familial dysalbuminemic hyperthyroxinemia (FDH). FDH is a form of euthyroid hyperthyroxinemia that is due to increased affinity of ALB for T(4). It is the most common cause of inherited euthyroid hyperthyroxinemia in Caucasian population. |
| Post-translational Modifications | Kenitra variant is partially O-glycosylated at Thr-620. It has two new disulfide bonds Cys-600 to Cys-602 and Cys-601 to Cys-606. Glycated in diabetic patients. Phosphorylation sites are present in the extracelllular medium. Acetylated on Lys-223 by acetylsalicylic acid. |
| Sequence Similarities | Belongs to the ALB/AFP/VDB family. Contains 3 albumin domains. |
Storage & Shipping
| Storage & Shipping | Store at -20°C. Please refer to protocols. |
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For research use only. Not for clinical use.
