Human Caprin 2(CAPRIN2) ELISA Kit (RMEK-0152432)
Cat. No.: RMEK-0152432
Category: ELISA Kits
INQUIRY
1 x 96 tests
This ELISA kit is a 1. 5 hour solid-phase ELISA designed for the quantitative determination of the targets. This ELISA kit for research use only, not for therapeutic or diagnostic applications!
Product Features
| Species Reactivity | Human |
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| Assay Time | 1.5 h |
Target Information
| Target Symbol | CAPRIN2 |
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| UniProt ID | Q6IMN6 |
| Biomarker of SCs/CSCs | Non Small Cell Lung Cancer |
| Function | Promotes phosphorylation of the Wnt coreceptor LRP6, leading to increased activity of the canonical Wnt signaling pathway. Facilitates constitutive LRP6 phosphorylation by CDK14/CCNY during G2/M stage of the cell cycle, which may potentiate cells for Wnt signaling. May regulate the transport and translation of mRNAs, modulating for instance the expression of proteins involved in synaptic plasticity in neurons (By similarity). Involved in regulation of growth as erythroblasts shift from a highly proliferative state towards their terminal phase of differentiation. May be involved in apoptosis. |
| Cellular Localization | [Isoform 1]: Cytoplasm. [Isoform 2]: Mitochondrion. Cytoplasm. Expressed throughout the cytoplasm. [Isoform 5]: Mitochondrion. Colocalizes with aggregated mitochondria. Cell membrane; Peripheral membrane protein. |
| Development Stage | Expression is highly regulated during erythroid development with increased expression at the stage of differentiation associated with the onset of global nuclear condensation and reduced cell proliferation. |
| Domain | The C1q domain is essential for the function in Wnt signaling. |
Storage & Shipping
| Storage | Store at 2-8°C |
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| Shipping | Gel Packs |
| Stability | The stability of kit is determined by the loss rate of activity. The loss rate of this kit is less than 5% within the expiration date under appropriate storage condition. |
For research use only. Not for clinical use.
