Human CD40 Antibody Pair - BSA and Azide free (RMAB-0252122)
Cat. No.: RMAB-0252122
Category: Antibody Pair
INQUIRY
10 x 96 tests
The Antibody Pair can be used to quantify Human CD40. BSA and Azide free antibody pairs include unconjugated capture and detector antibodies suitable for sandwich ELISAs. The antibodies are provided at an approximate concentration of 1 mg/mL as measured by the protein A280 method. The recommended antibody orientation is based on internal optimization for ELISA-based assays. Antibody orientation is assay dependent and needs to be optimized for each assay type. Both capture and detector antibodies are rabbit monoclonal antibodies delivering consistent, specific, and sensitive results._x000D_
Product Features
| Conjugate | Unconjugated capture and detector antibodies |
|---|---|
| Species Reactivity | Human |
| Range | 15.61 pg/mL - 1000 pg/mL |
| Applications | Sandwich ELISA |
| Key Features | Unconjugated capture and detector antibodies; Adaptable to any antibody pair-based assay format; Antibody concentration ~ 1 mg/mL; BSA and azide free buffer - ready for conjugation; Reacts with: Human |
Target Information
| Target Symbol | CD40 |
|---|---|
| Target Name | Tumor necrosis factor receptor superfamily member 5 |
| UniProt ID | P25942 |
| Cellular Localization | Secreted and Cell membrane. |
| Function | Receptor for TNFSF5/CD40LG. |
| Involvement in Disease | Defects in CD40 are the cause of hyper-IgM immunodeficiency syndrome type 3 (HIGM3); also known as hyper-IgM syndrome 3. HIGM3 is an autosomal recessive disorder which includes an inability of B cells to undergo isotype switching, one of the final differentiation steps in the humoral immune system, an inability to mount an antibody-specific immune response, and a lack of germinal center formation. |
| Sequence Similarities | Contains 4 TNFR-Cys repeats. |
Storage & Shipping
| Storage & Shipping | Store at 4°C. Please refer to protocols. |
|---|
For research use only. Not for clinical use.
