Human CD40 ELISA Kit (RMEK-0152470)
Cat. No.: RMEK-0152470
Category: ELISA Kits
INQUIRY
1 x 96 tests
This ELISA kit is a 1. 5 hour solid-phase ELISA designed for the quantitative determination of the targets. This ELISA kit for research use only, not for therapeutic or diagnostic applications!
Product Features
| Species Reactivity | Human |
|---|---|
| Assay Time | 1.5 h |
Target Information
| Target Symbol | CD40 |
|---|---|
| UniProt ID | P25942 |
| Function | Receptor for TNFSF5/CD40LG. Transduces TRAF6- and MAP3K8-mediated signals that activate ERK in macrophages and B cells, leading to induction of immunoglobulin secretion (By similarity). |
| Cellular Localization | [Isoform I]: Cell membrane; Single-pass type I membrane protein. [Isoform II]: Secreted. |
| Involvement in Disease | Immunodeficiency with hyper-IgM 3 (HIGM3): A rare immunodeficiency syndrome characterized by normal or elevated serum IgM levels with absence of IgG, IgA, and IgE. It results in a profound susceptibility to bacterial infections. The disease is caused by variants affecting the gene represented in this entry. |
Storage & Shipping
| Storage | Store at 2-8°C |
|---|---|
| Shipping | Gel Packs |
| Stability | The stability of kit is determined by the loss rate of activity. The loss rate of this kit is less than 5% within the expiration date under appropriate storage condition. |
For research use only. Not for clinical use.
