Human Hematopoietic Cells Expansion Medium - AOF (RMMS-00560188)
Cat. No.: RMMS-00560188
Category: Specialized Medium
Research Area: Cell Therapy Research, Stem Cell Biology, Transplantation Research
INQUIRY
500 mL
1 L
cGMP medium, for culture and expansion of human hematopoietic cells
Product Features
| Overview | This is an animal origin-free (AOF) medium that has been developed for the in vitro culture and expansion of human hematopoietic cells, when appropriate growth factors/cytokines and supplements (e. g. small molecules) are added. This allows users the flexibility to prepare medium that meets their requirements. -AOF contains only recombinant proteins and synthetic components, and does not contain serum or other human- or animal-derived components. -AOF has also demonstrated a higher capacity than other commercially available media for the expansion of both CD34⁺CD90⁺CD45RA⁻ and CD34brightCD90⁺CD45RA⁻ subsets, enriched for hematopoietic stem cells. CD34+ cells from cord blood expanded in -AOF for 7 days demonstrated similar or higher repopulation than uncultured cells when transplanted into sub-lethally irradiated NSG mice and measured at both short- (3 week) and long-term (20 week) engraftment timepoints. Please note, -AOF was originally launched as -ACF Without Phenol Red. This name change signifies that in addition to being animal component-free, no materials of animal or human origin are used in the manufacture of this medium or its components, to at least the secondary level of manufacturing. This medium also replaces -ACF. -AOF is manufactured under relevant cGMPs, ensuring the highest quality and consistency for reproducible results. |
|---|---|
| Species | Human |
| Cell Type | Hematopoietic Stem and Progenitor Cells |
| Applications | Cell Culture, Differentiation, Expansion, Genome Editing |
| Formulation | Animal Origin-Free, Serum-Free, Xeno-Free |
Storage & Shipping
| Storage | -20°C or colder |
|---|---|
| Shipping | Shipped on gel packs. |
For research use only. Not for clinical use.
