Human β-NGF Mini ABTS ELISA Development Kit (RMEK-0153032)
Cat. No.: RMEK-0153032
Category: ELISA Kits
INQUIRY
1 x 96 tests
Human β-NGF ELISA development kit contains the key components required for the quantitative measurement of natural and/or recombinant human β-NGF in a sandwich ELISA format. Using the ELISA protocol, the recommended microplates, reagents and solutions, the components supplied in this kit are sufficient to assay human β-NGF in approximately 200 ELISA plate wells.
Product Features
| Species Reactivity | Human |
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Target Information
| Target Symbol | NGF |
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| UniProt ID | P01138 |
| Function | Low affinity receptor which can bind to NGF, BDNF, NTF3, and NTF4. Forms a heterodimeric receptor with SORCS2 that binds the precursor forms of NGF, BDNF and NTF3 with high affinity, and has much lower affinity for mature NGF and BDNF. Plays an important role in differentiation and survival of specific neuronal populations during development (By similarity). Can mediate cell survival as well as cell death of neural cells. Plays a role in the inactivation of RHOA. Plays a role in the regulation of the translocation of GLUT4 to the cell surface in adipocytes and skeletal muscle cells in response to insulin, probably by regulating RAB31 activity, and thereby contributes to the regulation of insulin-dependent glucose uptake (By similarity). Necessary for the circadian oscillation of the clock genes BMAL1, PER1, PER2 and NR1D1 in the suprachiasmatic nucleus (SCmgetaN) of the brain and in liver and of the genes involved in glucose and lipid metabolism in the liver. |
| Cellular Localization | Cell membrane; Single-pass type I membrane protein. Perikaryon. Cell projection, growth cone. Cell projection, dendritic spine. |
| Domain | The death domain mediates interaction with RANBP9 (By similarity). It also mediates interaction with ARHGDIA and RIPK2. The extracellular domain is responsible for interaction with NTRK1. |
| Post-transcriptional Modifications | N- and O-glycosylated. O-linked glycans consist of Gal(1-3)GalNAc core elongated by 1 or 2 NeuNAc. Phosphorylated on serine residues. |
Storage & Shipping
| Storage | Store at 2-8°C |
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| Shipping | Gel Packs |
| Stability | The stability of kit is determined by the loss rate of activity. The loss rate of this kit is less than 5% within the expiration date under appropriate storage condition. |
For research use only. Not for clinical use.
