Human Recombinant CNTF

Ciliary neurotrophic factor. CNTF plays an important role in neurogenesis and the differentiation of neural stem cells and has been s μggested to possess a therapeutic role in treating neurological disorders. CNTF has also been shown to protect rod photoreceptors from light-induced damage and to have therapeutic effects on retinal degenerative diseases caused by genetic defect or damage induced by toxins, autoantibodies, or strong light. Another therapeutic role of CNTF has been reported in protecting oligodendrocytes from death induced by apoptosis. Additionally, CNTF is commonly used to differentiate human pluripotent stem cell (hPSC)-derived neural progenitor cells into astrocytes (Krencik & Zhang).